Research and development professionals worldwide are currently facing a perfect storm of supply issues. Costs are soaring, capacity is reduced, paperwork is tricky, and products are routinely getting stuck in customs queues for significant periods of time. To top it off, COVID-19 lockdowns and the ongoing conflict in Ukraine have damaged supply chain reliability even further. With chemical supply chains strained to an unprecedented level, could now be the perfect time to seek help from…
Introduction Researchers have an increasingly powerful set of cheminformatics tools that they can use to construct and refine libraries of compounds to match complex, multi-parametric sets of data and property values. Similarity searching, clustering, and filtering can all help explore chemical space and reduce an overwhelmingly large set of potential structures to a more manageable subset of representative compounds that might be synthesized or acquired. Time and budgets are key factors in research projects, so…
Compound availability is worse than you suspect. Read on… Two years ago, as COVID-19 was rapidly spreading around the world, in the MolPort logistics warehouse parcels were piling up as our clients’ labs were closing for lockdowns. Even though we started this year with the most intense COVID-19 wave yet, we felt a certain optimism for the year ahead as the end of this pandemic and its lockdowns seemed near. These past two years were…
Chemical Sourcing in Drug Discovery and Controlled Substances A controlled substance is generally a compound that has its manufacture, acquisition, possession and use regulated by a government. In drug screening, controlled compounds may be extremely difficult, if not impossible, to acquire. Moreover, the storage, handling, and disposal of controlled compounds can be further challenging still. Therefore, identifying controlled compounds early-on in the process, and removing them from the compound library list can help streamline chemical…
Are you placing at least five building block or screening compound orders in a month? From emailing procurement for purchase approval and requesting quotes, to waiting for order confirmation and manually submitting POs to suppliers to align with internal procurement requirements. There’s a lot of manual effort required on your behalf! Punchout catalogues, also known as PunchOut websites, are a method that allows you – the purchaser – to buy from a supplier’s website from…
Latvian company, MolPort, recently celebrated its 15-year anniversary – and what a 15-years it has been! MolPort was established with a clear mission: to deliver simpler, smarter chemical compound sourcing and procurement, and in turn reduce the enormous time, cost, and effort spent by laboratories trying to find reliable suppliers. Fifteen years ago, the compound procurement landscape looked very different compared to now. It was inconvenient at best and chaotic and fraught with risk at…
The current worrying situation in Ukraine requires patience. We are looking for the best way to continue providing a great sourcing service while coping with the difficulties posed by the Russian military invasion of Ukraine. With our beliefs as a guide, we are carefully evaluating our supplier list so we only include suppliers that fully abide by global regulations and support MolPort values. We are using the following rules to evaluate the MolPort Supplier list…
Chemical procurement of a large compound library for drug screening can be a more complex task than it first appears. The process can be time-consuming, requiring the right team and expertise, defining your compound library list, and handling supplier negotiations, logistics, formatting, and budget concerns. In this overview, we take you through the chemical procurement workflow for drug screening libraries start to finish, identifying the challenges at each stage and how you can implement strategies…
If the products are not delivered or you are not satisfied with quality, we can help fix it. The guarantee applies to products purchased from any seller at MolPort and covers up to USD 2000. The MolPort Guarantee may protect a buyer purchasing products via the MolPort where the payment for the products is made via MolPort and: The products are not delivered to the buyer (and they will be deemed to be undelivered if…
Designing a suitably diverse, yet specifically targeted set of available compounds to explore a new structure-activity relationship or validate a new bioassay is getting easier – with new smart SAR and assay design tools developed in-house or available from open-source sites and commercial software vendors. So far, so good. But where will you find these compounds and get them delivered, ready to run through your new bank of bioassay types? Surely that’s the easy part…
